If God knows every grain of sand and each hair on my head (and everyone else's head too), then I know He is with me. He know my heart, my loneliness, and sadness.
"Are not two sparrows sold for a farthing? And one of them shall not fall to the ground without your Father knoweth it.
And the very hairs of your head are all numbered. Fear ye not, therefore: ye are of more value than many sparrows." Matthew 10:26-27